Ligand binding reaction relaxation kinetics

Temperature-jump relaxation and the stopped-flow methods are suitable to follow the concentration changes over extremely short time intervals. Such studies have indicated that immune reaction kinetics resemble other biological systems in which ligands are bound to proteins (Weber, 1975) in that the binding strength of small molecules is largely dictated by the constant. The association rate constants ka, are very similar for various antibody-antigen systems, i.e., for... 

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