Lichrosphere beads

Plunkett and Arnold [3] reported imprinted supports based on metal-chelate interactions made in the pores of 10 pm Lichrosphere beads. These were highly stable, even after prolonged use for several hundred hours, and achieved reasonable separations of related Z w-imidazole model compounds. Unfortunately no direct comparison with the performance of bulk-imprinted material was presented. A photograph of part of a silica bead containing imprinted polymer is shown in Fig. 12.1. 

Fig. 12.1. Electron micrograph of part of a 10 /im Lichrosphere bead containing imprinted polymer in its pores (from [3]).

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