LH-Azonin

A soln. of K-/er -butoxide in er -butanol added at 50° to a mixture of the startg. chlorolactam and er/-butanol, refluxed overnight, and the product isolated via the cupric salt with subsequent removal of Cu(II)-ions as cupric 8-hydroxyquino-linate octahydro-lH-azonine-2-carboxylic acid. Y 80%. F. e. s. H. T.Naga-sawa et al., J. Med. Chem. 14, 501 (1971). 

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