Lerl-Butyl alcohol

Free ct/dohexene from peroxides by treating it with a saturated solution of sodium bisulphite, separate, dry and distil collect the fraction, b.p. 81-83°. Mix 8 2 g. of cydohexene with 55 ml. of the reagent, add a solution of 15 mg. of osmium tetroxide in anhydrous lerl.-butyl alcohol and cool the mixture to 0°. Allow to stand overnight, by which time the initial orange colouration will have disappeared. Remove the solvent and unused cydohexene by distillation at atmospheric pressure and fractionate the residue under reduced pressure. Collect the fraction of b.p. 120-140°/15 mm. this solidifies almost immediately. RecrystaUise from ethyl acetate The yield of pure cts-1 2-cydohexanediol, m.p. 96°, is 5-0 g. 

Fig. 24. Dependences of the initial rate of TBA formation and ratio of DIP/TBA on H3PMo,2O40 concentration in the hydration of butenes. TBA, lerl-butyl alcohol DIB, diisobutylene. 357 K, isobutylene/1-butene = 1/1 (molar). (From Ref. 163.)...

Potassium metal. Instruct others to maintain a safe distance. Wear eye protection, laboratory coat, and nitrile rubber gloves. Cover with dry sodium carbonate or calcium carbonate, scoop into a dry plastic pail, and transport to fume hood.3 Behind a shield, add a little at a time to a large excess of dry lerl butyl alcohol. Allow it to stand for 24 hours, and then wash into the drain, diluting greatly with at least 50 times its volume of water.4... 

The aldehyde intermediate can be isolated if a leas puwerfu] reducintt agent such as lithiu.ni trt>lerl but0xyalurniiiii3n hydride is ii. ed in place of LiAlH. This reagent, which is obtained by reaction of LiAlK with 3 cciuiv-alente of lerl-butyl alcohol, is particularly effective far carrying out the partial reduction of acid chlorides to aldehyde (Section 19.2>. 

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