Leptosphaeria oraemaris

Guerriero, A., D Ambrosio, M., Cuomo, V., and Pietra, F., A novel, degraded polyketidic lactone, leptosphaerolide, and its likely diketone precursor, leptosphaerodione. Isolation from cultures of the marine ascomycete Leptosphaeria oraemaris (Linder), Helv. Chim. Acta, 74, 1445, 1991. 

A new crystalline substance known as leptosphaerin (4), a member of the D series of 2-aminohexoses, was identified in the mycelium of a marine Ascomycotina, Leptosphaeria oraemaris (Linder) (Leptosphaeriaceae) [48]. Its synthesis was performed and its absolute configuration determined [49,50]. 

Culmorin (65), a sesquiterpenoid, was identified from the mycelium of a common lignicolous marine Ascomycotina, Leptosphaeria oraemaris Linder (Leptosphaeriaceae). This substance had been previously found in terrestrial Fusarium [originally in Fusarium culmorin (W.G. Smith)] [94]. Its structure was elucidated in 1967 [95]. 

White, J.D., Badger, R.A., Kezar, H.S., Pallenberg, A.J., and Schiehser, G.A. (1989) Structure, synthesis and absolute configuration of leptosphaerin, a metabolite of the marine ascomycete Leptosphaeria oraemaris. Tetrahedron, 45, 6631-6644. 

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