Lecitase® Ultra

A porous vessel filled with the biocatalyst and immersed in recirculating toluene was applied for the preparation of methyl trans-(2 J ,3S)-(4-methoxyphenyl)glyddate (an intermediate of Diltiazem) from its racemic methyl ester [88]. In this system, hydrolysis of the ester with Lecitase Ultra (a commercially available phospholipase) immobilized in macroporous gelatin organo-gel (gelozyme) gave the desired product in 47% yield and >99% ee. 

Response surface methodology was used to optimize enzymatic rapeseed oil degumming process parameters (Yang et al., 2006). Lecitase Ultra was used to degum rapeseed oil. The optimal conditions were determined as follows enzyme dosage 39.6mg/kg, temperature... 

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