Lattice fibre network

Macroscopically, acute viral hepatitis presents as a large red liver (H. Kalk, 1947). The enlargement is probably due to hyperaemia and to the oedematization of the portal area. The reddening is brought about by hyperaemia and the accumulation of large quantities of stagnating erythrocytes in the empty lattice fibre network. 

Confluent liver cell necrosis, possibly developing into bridging necroses (32) or multilobular (< 3% of cases) or even massive necroses in B, B/D and C hepatitis, as well as in E hepatitis during pregnancy collapse of the lattice fibre network. Formation of passive septa, cholestasis, accumulation of ceroid and siderin in macrophages and stellate cells. 

---