Laser-targeted delivery

Figure 1 Principle of LTD. Schematic representation of heat and dye distribution during laser-targeted drug delivery following a laser pulse in an eye with CNV. The energy deposited in the tissues causes heating, as illustrated by the oval. The bolus of dye released in the CNV vessels is retained longer than that in the choriocapillaris because of slower flow within the CNV. The CNV and the tissues in its immediate vicinity reach the releasing temperature of the liposomes, but the retinal vessels do not. Abbreviations. LTD, laser-targeted delivery CNV, choroidal neovascularization. Source From Ref. 4, Figure 1.

FIGURE 15.16 Photomechanical wave delivery devices. A drug reservoir backed with a laser target material (e.g., black polystyrene) is placed on the skin. Laser-induced photomechanical waves are supposed to increase the permeability of the stratum comeum allowing the facilitated passage of drug molecules from the reservoir into the skin. (From Cross, S.E. and Roberts, M.S., Curr. Drug Deliv., 1, 81, 2004. With permission.)... 

METHODOLOGY OF LASER-TARGETED DRUG DELIVERY Principle of Laser-Targeted Drug Delivery... 

Laser-Targeted Drug Delivery to Retinal Tissues... 

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