Lamisil - Terbinafine hydrochloride

Lamisil Tablets (Terbinafine hydrochloride). Novartis Pharmaceuticals UK Ltd. UK Summary of product characteristics, February 2007. 

Naftifine hydrochloride and terbinafine (Lamisil) are allylamines that are highly active against dermatophytes but less active against yeasts. The antifungal activity derives from selective inhibition of squalene epoxidase, a key enzyme for the synthesis of ergosterol (see Figure 48-1). 

Terbinafine (Lamisil) is an allylamine with activity similar to that of naftifine hydrochloride. It is available as a 1% cream and solution for the topical treatment of dermatophyte infections. 

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