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Lamellar protrusion

The Locomotion of Amoeba The Locomotion of Fibroblastic Cell Types The Locomotion of Leukocytes The Behavior of Locomoting Cells The Role of the Cytoskeleton in Cell Locomotion The Microtubule-Based Cytoskeleton The Intermediate Filament-Based Cytoskeleton The Microfilament-Based Cytoskeleton The Organization of Microfilaments in Cells Microfilament Dynamics and Cell Locomotion Sites of Lamellar Protrusion May Be Determined by the Nucleation of Actin Polymerization... [Pg.77]

Sites of Lamellar Protrusion May Be Determined by the Nucleation of Actin Polymerization... [Pg.89]

Figure 4. The Brownian ratchet model of lamellar protrusion (Peskin et al., 1993). According to this hypothesis, the distance between the plasma membrane (PM) and the filament end fluctuates randomly. At a point in time when the PM is most distant from the filament end, a new monomer is able to add on. Consequently, the PM is no longer able to return to its former position since the filament is now longer. The filament cannot be pushed backwards by the returning PM as it is locked into the mass of the cell cortex by actin binding proteins. In this way, the PM is permitted to diffuse only in an outward direction. The maximum force which a single filament can exert (the stalling force) is related to the thermal energy of the actin monomer by kinetic theory according to the following equation ... Figure 4. The Brownian ratchet model of lamellar protrusion (Peskin et al., 1993). According to this hypothesis, the distance between the plasma membrane (PM) and the filament end fluctuates randomly. At a point in time when the PM is most distant from the filament end, a new monomer is able to add on. Consequently, the PM is no longer able to return to its former position since the filament is now longer. The filament cannot be pushed backwards by the returning PM as it is locked into the mass of the cell cortex by actin binding proteins. In this way, the PM is permitted to diffuse only in an outward direction. The maximum force which a single filament can exert (the stalling force) is related to the thermal energy of the actin monomer by kinetic theory according to the following equation ...
See other pages where Lamellar protrusion is mentioned: [Pg.80]    [Pg.81]    [Pg.88]    [Pg.89]    [Pg.206]    [Pg.128]    [Pg.80]    [Pg.81]    [Pg.88]    [Pg.89]    [Pg.206]    [Pg.128]    [Pg.90]    [Pg.616]    [Pg.138]    [Pg.201]    [Pg.324]    [Pg.506]    [Pg.212]    [Pg.114]    [Pg.219]   
See also in sourсe #XX -- [ Pg.80 ]

See also in sourсe #XX -- [ Pg.206 ]



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Lamellarity

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