Lactaranolide Derivatives

5-Lactaranolide derivatives included in Part 12 are produced by silica gel degradation of velutinal esters (7.28, 7.30), methylvelutinal (7.17) or free velutinal itself (for a discussion of these transformations see the chapter on chemical interconversions of Lactarius sesquiterpenes). The compounds upon acidification underwent aromatization to form furanoid derivatives (see Part 18). Under these conditions dehydration reactions took place and also dienes were formed (72). 

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Three examples of 8-keto-5-lactaranolides (11.1, 11.2, 11.4) as well as three examples of epoxy-derivatives (11.2, 11.14, 11.57) were isolated. 

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