L,N2-deoxyguanosine adduct

Rizzo, C.J., and Stone, M.P. (2009) Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) l,N2-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA. Chem. Res. Toxicol, 22, 187-200. 

Interstrand DNA Cross-Linking l,N2-Deoxyguanosine Adducts Derived from oc,p-Unsaturated Aldehydes ... 

Fernandes, P., Wang, H., Rizzo, C., and Lloyd, R. (2003) Site-specific mutagenicity of stereochemically defined l.N2-deoxyguanosine adducts of trans-4-hydroxynonenal in mammalian cells. Environ. Mol. Mutagen., 42, 68-74. 

Wang, H., Kozekov, I.D., Harris, T.M., and Rizzo, C.J. (2003) Site-specific synthesis and reactivity of oligonucleotides containing stereochemically defined l.N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-hydroxynonenal. J. Am. Chem. Soc., 125, 5687-5700. 

Douki, T. and Ames, B.N. (1994) An HPLC-EC assay for l,N2-propano adducts of 2 -deoxyguanosine with 4-hydroxynonenal and other a, 3-unsaturated aldehydes. Chem. Res. Toxicol, 7, 511-518. 

Shukla, R Jelinsky, S., Liu, T., Geactinov, N.E., and Loechler, E.L. (1997) How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzoJaJpyrene configuration of the adduct bond is more important than those of hydroxyl groups. Biochemistry, 36,13263-132639. 

Chung, F.L. and Hecht., S.S. (1983) Formation of cyclic l.N2-adducts by reaction of deoxyguanosine with a-acetoxy-N-nitrosopyrrolidine, 4-(carbethoxynitrosamino)butanal, or crotonaldehyde. Cancer Res., 43, 1230-1235. 

Douki, T., Odin, F., Caillat, S., Favier, A., and Cadet., J. (2004) Predominance of the l,N2-propano 2 -deoxyguanosine adduct among 4-hydroxy-2-nonenal-induced DNA lesions. Free Radio. Biol. Med., 37, 62-70. 

Riggins, J.N., Pratt, D.A., Voehler, M., Daniels, J.S., and Marnett, L.J. (2004) Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, N2-(3-oxo-l-propenyl)deoxyguanosine (N2OPdG-), to 3-(2 -deoxy-P-D-erythro-pentofuranosyl)pyrimido[l,2-a] purin-10(3ff)-one (M,dG). J. Am. Chem. Soc., 126,10571-10581. 

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