L-iodo-2-nitrobenzene

The electrochemically induced S l reaction of haloarenes with uracil anion (177) in DMSO gave 5-aryl uracils 178 in 30-55% yields (equation 123)227. Thus, good yields of the 5-aryl uracils were obtained in the reaction with 4-bromobenzophenone (55%), 4-chlorobenzonitrile (50%) and l-iodo-4-nitrobenzene (55%). With l-iodo-2-trifluoromethylbenzene (and with phthalonitrile as a redox catalysis), 30% of the 5-aryl uracil was formed. 

Palladium-catalyzed reactions can be used to connect the terminal end of an alkyne and aromatic iodide, as shown in the reaction below. They are useful in industry and are widely employed in the academic arena. The experiment presented here was adapted from an article by Goodwin, Hurst, and Ross. The mechanism shown is for the coupling of l-iodo-4-nitrobenzene with 1-pentyne. Small amounts of a dimer obtained from the coupling of the 1-alkynes are also formed in these... 

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