3-hydroxy-l-phenyl

Theoretical calculations on the 3-H tautomer of l-hydroxy-4-phenyl-5-carboxylic acid 443 (R4 = Ph, R5 = COOH) have been performed using the B3LYP/6-31G(d) (2005RJOC591) method. 

Hydrazone of 1 -hydrazino-1 -hydroxy-4-phenyl-1,2-dihydro-3//-pyrido [l,2-c]pyrimidin-3-one was patented as cross-linkers for making physiologically compatible and H2O insoluble hydrazine or hydrazono compounds (97JAP(K)97/59303). 

Dioxo-3-alkyl-imidazolidine werden mit Lithiumalanat in der Hitze zu 3-A1-kyl-imidazolidinen reduziert z.B. 2,4-Dioxo-3-methyl-5-phenyl-imidazolidin zu 7-Methyl-4-phenyl-imidazolidin (43% d.Th.) bei 23° und inverser Zugabe wird dagegen (vgl. S. 252) 2-Hydroxy-l-methyl-4-phenyl-imidazol (66% d. Th.) erhalten, das sich unter energischen Bedingungen zum 7-Methyl-4-phenyl-imidazol (25 % d. Th.) reduzieren laftt3 ... 

In 1969, Hromatka et al. <69M928> found that the cyclization of 5-chloro-2-(iV-methyl-iodomethanesulfonamido)-benzophenone 8 with ammonia or alcoholic ammonia gave 6-chloro-4-hydroxy-l-methyl-4-phenyl-3,4-dihydro-2,l-benzothiazine 2,2-dioxide 9 and 6-chloro-4-hydroxy-3-iodo-l-methyl-4-phenyl-3,4-dihydro-2,l-benzothiazine 2,2-dioxide 10 in 30% and 33% yields, respectively (Scheme 2). 

Figure 4 Cyclic voltammograms recorded at different scan rates of a CH2Cl2 solution of 1,1 bis( diphenylphosphino)-2-[ -(((l-hydroxy-2-phenyl) amino) me thylboro-nate) ethyl]ferrocene. Platinum working electrode. Supporting electrolyte [NBu4][C104] (0.2 mol dm 3)...

Anilinocarbonyl-l-hydroxy-4-methyl-2-phenyl-imidazol-3-oxid212 ... 

CO-NH-C12Hjs -cl 2- (4-Chlor-phenyl) -5-dodecylaminocarhonyl-l-hydroxy-4-methyl-... 97 180... 

Die Umlagerung von 2-Amino-5-methyl-3-(2-oxo-2-phenyl-ethyl)-1,3,4-oxadiazolium-broraid mit heiBer wiiBriger Kaliumcarbonat-Losung zu l-Acetylamino-2-hydroxy-4-phenyl-imidazol wurde bereits im Bd. X/2, S. 345 beschrieben. 

Applications of the Conrad-Limpach reaction to the synthesis of 1-hydroxy-4,7-phenanthrolines or, more correctly, l-oxo-l,4-dihydro-4,7-phenanthrolines, from p-phenylenediamine or 6-aminoquinolines continue to be reported. l,10-Dihydroxy-3,8-dimethyl-4,7-phenanthroline has again been prepared from p-phenylenediamine,234 hot diphenyl ether being used to effect the cyclization. Other examples include the new or improved preparations of l-hydroxy-3-methyl-, 10-amino-l-hydroxy-3-methyl-,232 2-(y-chlorocrotonyl)- l,10-dihydroxy-3,8-dimethyl-, and 2,9-bis (y- chlorocrotonyl)-1,10- dihydroxy - 3,8 - dimethyl - 4,7 - phenanthro-lines.235 Compounds prepared in this way have been patented as antiasthmatic agents.178 A closely related synthesis employing poly-phosphoric acid as cyclizing agent has yielded l-hydroxy-3-phenyl-4,7-phenanthroline.236... 

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