L- hexane

Figure 4. Products of acetolysis of bicyclo[2.1. l]hexane-5-methyl tosylates.

The submitters used silica gel (mesh 100-200, BW-820 MH) from Fuji Davison Chemical, Ltd. (Japan). The checkers used radial chromatography (silica gel 60 PF 254 with gypsum, EM Science) with hexane/ethyl acetate (4/1) as eluent for small scale reactions. The checkers used flash chromatography (240 g of silica gel, grade 633, 47 x 61 microns, Davison Chemical) with hexane (1.5 L), hexane/ether (10/1,1.5 L), and ether (1.5 L) as eluent for large scale reactions (100 mmol). 

Additional aldehydes and ketones were also included in the U.S. Nationwide Occurrence Study dimethylglyoxal (2,3-butanedione), cyanoformaldehyde, 2-butanone (methyl ethyl ketone), trans-2-hexanal, 5-keto-l-hexanal, and 6-hydroxy-2-hexanone [11, 13]. Dimethylglyoxal was the most consistently detected of these carbonyl compounds (up to 3.5 pg/L) and was found at higher levels in plants using ozone. Maximum levels of 0.3, 5.0, and 0.7 pg/L were observed for cyanoformaldehyde, 2-butanone, and trans-2-hexenal, respectively 6-hydroxy-2-hexanone and 5-keto-1 -hexanal were only detected in early stages of treatment, and not in finished waters. 

Under relatively forceful conditions, the rearrangement of l-bromo-7,7-dimethylbicy-clo[2.2.1]heptan-2-one with 2 M aqueous potassium hydroxide at 155 °C gave 5,5-dimethylbi-cyclo[2.1, l]hexane-l-carboxylic acid (2) in 79% yield.55... 

Exercise 11-8 Consider that it is necessary to synthesize pure samples of d.l-hexane-3,4-D2 and meso-hexane-3,4-D2. Show how this might be done both with diimide and catalytic-type reductions, assuming that any necessary deuterium-iabeled reagents and six-carbon organic compounds are available. 

One kg of the fine powdered marijuana plant material [average % of THC was about 5.21%] was macerated with 6 L hexanes (Hexanes GR from EM Sciences) in a percolator (9" in diameter from the top and 20" long, cone shaped) for 24 hours at room temperature and filtered. The macerate was reextracted with 5 L hexanes for another 24 hours. The hexane extracts were combined and evaporated under reduced pressure at low temperature to give 110.7 g residue (11.07% extractives). The % of THC in the hexane extract was 41.21%. 

Das Bicyclo[2,l.l]hexan-Derivat 38 mit der gleichen Stereochemie wie in 36 stellt 90 % des fliichtigen Produktes der durch Benzophenon sensi-bilisierten Isomerisierung des Nerylacetats (Formel 37) (70) dar. Ebenso laBt sich l,5-Hexadien-3-on (Formel39) glatt in Bicyclo[2,l,l]hexan-2-on (Formel 40) uberfuhren (26). 

Dimethyl-l-vinylbicyclo[2,l,l]hexan (Formel 68) stellt das Resultat der Bestrahlung einer 5-proz. Losung von Myrcen (Formel 67) in Hexan. oder Benzol in Gegenwart von Benzophenon, (3-Acetonaphthon oder Fluorenon dar (182). 3,3-Dimethyl-l-vinyl-bicyclo[2,2,0]hexan (Formel 69) bildet sich nicht (vgl. Photoisomerisierung des Citrals, S. 497). 

The conversion product tetra(carbahexa)borane 167 (molecular structure shown in Fig. 8) can be obtained from diborane 165 (Scheme 26) via a 2,5-diborabicyclo-[2,l,l]-hexane 166 and its structure have been reported by Enders et al.104 Synthesis of carbaboron compounds has also been reviewed previously.105,106... 

Propellane (94) was synthesized from l,4-diiodobicyclo[2 l.l]hexane (93) using potassium vapor and isolated in a nitrogen matrix It was tentatively identified on the basis of its infrared spectrum. The paper includes a table of infrared frequencies for... 

We now turn to the reaction of 6-bromo-l-hexane 110 with magnesium in THF in the presence of DCPH, studied by Ashby and Oswald [77] (Scheme 47). Comparing the result with the earlier discussion in Section III.E.2, it is clear that all radicals that escaped the magnesium surface were trapped by DCPH, which for the hexenyl radical was no more than 25%. The formation of cyclized hydrocarbon 112 (4.7%) was ascribed to cyclization occurring at the surface, since a hexenyl radical leaving the surface was expected to react with DCPH before it could cyclize. 

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