L-Chloro-3-iodobenzene

One year later, in 2006, Hu and Tang reported that Pd(OAc)2/PtBu3 is another active system for the transformation of o-alkynylhaloarenes. By using KOtBu as a base in toluene, the corresponding indoles were produced in excellent yields by coupling with various amines. With l-chloro-2-iodobenzene... 

When used in THF, Li(TMP)Al(i-Bu)j (2 equiv) is capable of deprotonating substituted benzenes such as anisole and A,A-diisopropylbenzamide at room temperature and sensitive substrates such as benzo-nitrile and l-chloro-4-iodobenzene at -78°C. Iodine is the electrophile of choice, but others can also be... 

However, neither copper(I) iodide nor photostimulation are absolutely necessary for the arylation of benzenetellurolate. Lithium benzenetellurolate and 1,2-bromoiodobenzene condensed in tetrahydrofuran at 20° to form 1,2-bis phenyltelluro benzene in 32% yield. Sodium benzenetellurolate condensed similarly with 1-chloro-2,4-dinitrobenzene at 20° in tetrahydrofuran/aqueous sodium hydroxide in the presence of a phase-transfer reagent. In this case 2,4-dinitrophenyl phenyl tellurium (m.p. 134°) was isolated in 30% yield d. Lithium methanetellurolate was arylated in tetrahydrofuran by iodobenzene, 1,2-dibromobenzene, and l-bromo-2-methoxybenzene at 20°. ... 

Biphenyls (entry 1) [84] or styrene derivatives (entries 2-4) [85], p-terphenyls (entry 5) [86], and m-terphenyls (entries 6-9) [87, 88] are synthesized from 2-bro-mo-1-iodobenzene, 2,5-dibromo-l,4-diiodobenzene, and 2,6-dibromo- or 2,6-di-chloro-1-iodobenzene, respectively, in moderate to good yields. 

Which step(s) in the multistep synthesis of l-bromo-3-chloro-5-iodobenzene from benzene is/are ... 

Benzil-a-aiylimino oximes 292 (Aggarwal et al. 2006) and a-nitroketene N.S-anilinoacetals 297 (Venkatesh et al. 2005), containing a C-C-N fragment at the aniline nitrogen atom when exposed to, respectively, iodobenzene diacetate Phi (OAc)2 (IBD) and POCI3, undergo cyclization with the formation of the 2,3-diphenylquinoxaline-l-oxide 293 (Scheme 2.51) and 3-chloro-2-(methylthio) quinoxaUne 298 (Scheme 2.52) derivatives, respectively. 

Common Name 2-Chloroiodobenzene Synonym 2-chloro-l-iodobenzene Chemical Name ... 

Senn and Ziegler find the dissociative pathway to be the preferred one in their calculations in THF solution of the oxidative addition of chloro-, bromo- and iodobenzene to Pd(P-P) complexes, where P-P is a chelating diphosphine ligand of the type l,2-bis(dimethylphosphino)ethane or (P)-2,2 -bis(dimethylphosphino)-1,1 -biphenyl. The barriers from the prereaction complex are in fact quite low 31, 12 and 5 kJ/mol for the chloro, bromo and iodo species, respectively. For methyl-(lS,5R)-5-chlorocyclohex-3-ene-l-carboxylate in presence of neutral palladium, Espinet and Echavarren observed retention of configuration in apolar solvent (benzene) and inversion in polar solvent (acetonitrile) [13]. 

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