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L-acetylcarnitine

L-acetylcarnitine is produced naturally in the CNS and indirectly stimulates acetylcholine production, as well as purportedly modulating cerebral metabolism. A study of nearly 500 geriatric patients in Italy provided evidence that L-acetylcarnitine... [Pg.208]

Salvioli G and Neri M (1994). L-acetylcarnitine treatment of mental decline in the elderly. Drugs, Experimental and Clinical Research, 20, 169-176. [Pg.281]

L-Acetylcarnitine is a endogenous substance, synthesized in the mitochondria, that increases cellular oxidative metabolism and cholinergic activity. It has a good penetration in the CNS when administered orally and intravenously, and no side effects have been observed. L-Acetylcarnitine has a large variety of interesting pharmacological properties ... [Pg.513]

In a 1-year study of 130 patients with AD [63 in treatment with L-acetylcarnitine and 67 with placebo], an improvement in the cognitive decline measured through neuropsychiatric batteries was observed [Spagnoli et al. 1991]. [Pg.513]

Campi N, Todeschini GP, Scarzella L (1990) Selegiline versus L-acetylcarnitine in the treatment of Alzheimer-type dementia. Clin Ther 12 306-314... [Pg.148]

Villa, R.F. and Gorini, A. (1991) Action of L-acetylcarnitine on different cerebral mitochondrial populations from hippocampus and striatum during aging. Neurochem. Res. 16 1125-1132. [Pg.508]

Masterson, C. Wood, C. and Thomas, D.R. (1990a) L-acetylcarnitine, a substrate for chloroplast fatty acid biosynthesis. Plant Cell Envir., 13, 755-765. [Pg.77]

Acetylcarnitine chloride [R 5080-50-2][S 5061-35-8][RS 2504-l 1-2] M 239.7. Recrystd from isopropanol. Dried over P2O5 under high vacuum. [Pg.71]

Figure 55-14 Plasma profiles of plasma acylcarnitine butyl-ester derivatives. A, Normal control. B, Propionic acidemia. C, Short-chain acyl-CoA dehydrogenase deficiency. D, Isovaleric acidemia. E, Medium-chain acyl-CoA dehydrogenase deficiency. F, Very long-chain acyl-CoA dehydrogenase deficiency. G, Long-chain L-3-hydroxy acyl-CoA dehydrogenase deficiency.The symbol marks internal standards [ Hjj-acetylcarnitine (m/z 263) [ HaJ-propionylcarnitine (m/z 277) fH ]-butyrylcarnitlne (m/z 295) pHal-octanoylcarnitine (m/z 347) [ Haj-dodecanoylcarnltine (m/z 403) [ Haj-palmitoy I carnitine (m/z 459). Figure 55-14 Plasma profiles of plasma acylcarnitine butyl-ester derivatives. A, Normal control. B, Propionic acidemia. C, Short-chain acyl-CoA dehydrogenase deficiency. D, Isovaleric acidemia. E, Medium-chain acyl-CoA dehydrogenase deficiency. F, Very long-chain acyl-CoA dehydrogenase deficiency. G, Long-chain L-3-hydroxy acyl-CoA dehydrogenase deficiency.The symbol marks internal standards [ Hjj-acetylcarnitine (m/z 263) [ HaJ-propionylcarnitine (m/z 277) fH ]-butyrylcarnitlne (m/z 295) pHal-octanoylcarnitine (m/z 347) [ Haj-dodecanoylcarnltine (m/z 403) [ Haj-palmitoy I carnitine (m/z 459).
See other pages where L-acetylcarnitine is mentioned: [Pg.244]    [Pg.513]    [Pg.244]    [Pg.513]    [Pg.506]    [Pg.189]    [Pg.194]    [Pg.506]    [Pg.583]    [Pg.13]    [Pg.385]    [Pg.772]    [Pg.772]    [Pg.76]    [Pg.410]    [Pg.348]    [Pg.536]   


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