L,2,3,3a,4,5-Hexahydro

A wide variety of alkaloids have been synthesized by this procedure although in many cases the chemical yields are low. Hexahydroapoerysopine (353), for example, has been prepared by irradiation in dioxane of either the 6 -iodo or the 7-bromo derivative of l,2,3,3a,4,5-hexahydro-/V-(3,4-di-... 

It is seen that initially 4,5-dihydropyrene (31), 1,2,3,6,7,8-hexhydro(,s-hexahy-dro)pyrene (33), and l,2,3,3a,4,5-hexahydro(a,s -hexahydro)pyrene (34) are formed simultaneously from pyrene. The most part (78%) of initially formed 31 is hydrogenated to the tetrahydro derivative 32 rather rapidly. The hydrogenation of 32 is very slow under these conditions, and it has been shown that it is isomerized largely... 

Substituted 5-[(2,6-Dimethylphcnyl)imino]-l,2,3,3a,4,5-hexahydro-2,2-dimethylpentalenes 3 General Procedure7 ... 

Die reduktive Cyclisierung der 3-[Chinoxalinyl-(2)]-propensaure zum 1-Oxo-l,2,3,3a,4,5-hexahydro-(pyrrolo-[l, 2-a]-chinolaxin) setzt die Bildung eines se-kundaren cyclischen Amins voraus, die unter milden Bedingungen mit Raney-Nickel (100 Gew.% bez. auf das Substrat) gelingt12. 

---