Kreysigia multiflora

Specifically C-labeled 1 -phenethylisoquinolines were administered to Kreysigia multiflora plants, and the alkaloids were isolated and degraded to unambiguous sequences. The results show that the C-homoaporphine... 

Of the homoproaporphine alkaloids kreysiginone (19), dihydro-kreysiginone (21), and bulbocodine (22), the former two (19 and 21) were isolated from Kreysigia multiflora (2a). The last was isolated from Bulhocodium vernum (16) and its structure has been determined recently by Santavy (17). 

Some years ago, three alkaloids, namely, kreysigine (31a), floramul-tine (32), and multifloramine (33), were isolated from Kreysigia multiflora 6, 20). Recently, a fourth alkaloid, (— )-kreysigine (31b) was isolated from Bvlbocodium vernum (17). The chemical behavior of this alkaloid has not been described. 

In order to distinguish between these possibilities, the [3- C] diphenolic isoquinolines 77a,b,c were administered to Kreysigia multiflora shoots which converted the homoaporphines 79a,b,c,d into... 

Before kreysiginone was isolated from a natural source diphenolic isoquinoline 76 had been oxidized with ferric chloride to yield homo-proaporphines 19 and 20 (40), one of which, dienone 19, was isolated from Kreysigia multiflora by Battersby (2a). Battersby also synthesized both dienones 19 and 20 by the same reaction of 76 with potassium ferricyanide. In this reaction he examined the phenol oxidation of the diphenolic isoquinoline 86 and obtained product 87 containing... 

Homoaporphine Alkaloids.—Full details of the research on the biosynthesis of the homoaporphine alkaloids of Kreysigia multiflora have been published. In essence there is no information additional to that published in preliminary form and reviewed. ... 

Oberlin-Zeisel reaction (Rgt. No. 102) yields brown-blue. Isolated from Kreysigia multiflora,... 

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