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Kinase substrate-induced cleft closing

This type of behavior is consistent with the induced-fit theory of enzyme action (Section 6.4). In all kinases for which the structure is known, a cleft closes when substrate is bound. [Pg.499]


See other pages where Kinase substrate-induced cleft closing is mentioned: [Pg.648]    [Pg.437]    [Pg.430]    [Pg.647]    [Pg.647]    [Pg.229]    [Pg.76]    [Pg.428]    [Pg.83]    [Pg.134]   


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Clefts

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