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Kidney drug targeting

Wang Y, Sun Y, Wang H, Liu P, Peng W, Duan Y (2013). thesis of low-molecular weight protein (LMWP) lysozyme-curcumin conjugates for kidney drug targeting. J Biomater Sci Polym Ed, 24, 1360-1367. [Pg.623]

Figure 5.7. Schematic representation of the mechanism by which drug targeting to the proximal tubular cell of the kidney might be achieved using a low molecular weight protein (LMWP) as a carrier. Figure 5.7. Schematic representation of the mechanism by which drug targeting to the proximal tubular cell of the kidney might be achieved using a low molecular weight protein (LMWP) as a carrier.
Beta-lactam antibiotics (pencillins, cephalosporins, and carbapenems) are excreted by the kidneys and hence the kidneys are targets of toxicity. These drugs can cause interstitial nephritis, tubular necrosis, and allergic angitis. Beta-lactams behave like haptens which are then... [Pg.565]

Flolly MK, Dear JW, Flu X, Schechter AN, Gladwin MT, Flewitt SM, Yuen PS, Star RA Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure. Kidney International 70 496-506, 2006... [Pg.209]

Brandt I, Eund J, Bergman A, et al. 1985. Target cells for the polychlorinated biphenyl metabolite 4,4 -bis(methylsulphonyl)-2,2, 5,5 -tetrachlorobiphenyl in lung and kidney. Drug Metab Dispos 13 490-496. [Pg.715]

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See also in sourсe #XX -- [ Pg.124 , Pg.135 ]



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