Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Kidney cancer drugs that cause

For drugs that have poor oral bioavailability, rectal administration of prodrugs can increase their absorption. For example, nalbuphine is an analgesic with potency approximately 0.5-0.9 that of morphine. It is used for the relief of moderate to severe pain from a variety of causes, e.g., surgery, trauma, cancer, kidney, or biliary colic pain. Oral bioavailability of nalbuphine was poor, e.g., around 6% in experimental dogs. Rectal administration of nalbuphine-3-acetylsalicylate in the same animals enhanced the bioavailability 4- to 5-fold to around 28%. In addition, the plasma half-life of nalbuphine after rectal administration of the prodrug was prolonged. [Pg.310]


See other pages where Kidney cancer drugs that cause is mentioned: [Pg.178]    [Pg.1292]    [Pg.1293]    [Pg.367]    [Pg.412]    [Pg.235]    [Pg.73]    [Pg.581]    [Pg.1245]    [Pg.1290]    [Pg.44]    [Pg.349]    [Pg.52]    [Pg.107]    [Pg.545]    [Pg.5]    [Pg.152]    [Pg.477]    [Pg.581]    [Pg.1245]    [Pg.721]    [Pg.721]    [Pg.436]    [Pg.800]    [Pg.81]    [Pg.304]    [Pg.166]    [Pg.149]    [Pg.144]    [Pg.417]    [Pg.436]    [Pg.275]    [Pg.424]    [Pg.95]    [Pg.98]    [Pg.979]    [Pg.207]    [Pg.795]    [Pg.180]    [Pg.101]    [Pg.76]   
See also in sourсe #XX -- [ Pg.228 ]




SEARCH



Cancer causes

Cancer causing drugs

Kidney cancer

© 2024 chempedia.info