Khivorin derivatives

The chemical shifts of methyl groups in a series of khivorin derivatives have received detailed comment. 

In compounds of this group, the B ring of khivorin derivatives is opened to a lactone or ester, apparently by oxidation of a 7-keto compound, without the formation of any subsequent carbon ring. This has been done in the laboratory by Baeyer-Villiger oxidation and andirobin (37) has been partially synthesised (74, 76) (Scheme 6). When a suitable derivative is prepared, cyclisation occurs spontaneously to give a l,14 oxide this can be formed from either a -hydroxy or a 14-hydroxy compound... 

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See also in sourсe #XX -- [ ]

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