Key features and side effects of antidepressant medications

Dosing required Sedation gain dysfunction effects 

Anticholinergic effects, orthostasis, quinidine-like effects on cardiac conduction lethal in overdose 

Initial nausea, loose bowel movements, headache, insomnia Initial nausea, headache, insomnia, anxiety or agitation seizure risk Similar to SSRI side effects dose-dependent hypertension 

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TABLE 2-3. Key features and side effects of antidepressant medications... 

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