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Key Concepts—Aldehydes and Ketones—Nucleophilic Addition

The reaction is reversible. Equilibrium favors the product only with less stable carbonyl compounds (e.g., H2CO and CI3CCHO). [Pg.815]

Step [1] is best with CH3X and RCH2X because the reaction follows an Sn2 mechanism. [Pg.815]

A strong base is needed for proton removal in Step [2]. [Pg.815]

The reaction is acid cataiyzed and is the reverse of acetai synthesis. [Pg.815]

A large excess of H2O drives the equiiibrium to favor the products. [Pg.815]


See other pages where Key Concepts—Aldehydes and Ketones—Nucleophilic Addition is mentioned: [Pg.814]    [Pg.815]   


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Addition aldehydes

Addition ketones

Additional Concepts

Additivity, concept

Aldehydes nucleophiles

Aldehydes nucleophilic addition

And nucleophilic addition

Ketones nucleophiles

Ketones nucleophilic addition

Key Additives

Key concepts

Nucleophiles aldehydes and ketones

Nucleophilic addition aldehydes and ketones

Nucleophilic addition aldehydes/ketones

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