Kaiser resin 4-nitrobenzophenone oxime

A further type of linker, especially designed for facile nucleophilic cleavage, is the oxime linker. Oximes of resin-bound ketones or aldehydes can be acylated to yield O-acyl oximes, which are readily cleaved by a variety of nucleophiles (Table 3.14). A widely used support of this type is p-nitrobenzophenone oxime resin (Kaiser oxime... 

Kaiser oxime resin cross-linked polystyrene with 4-nitrobenzophenone oxime linker Lawesson s reagent 2,4-bis(4-methoxyphenyl)-l, 3-dithia-2,4-diphosphetane-2,4-disulfide... 

Kaiser oxime resin, 4-nitrobenzophenone oxime resin, a base-labile resin widdy used for the synthesis of Boc/Bzl-protected segments. Several methods have been de-... 

Fin 1989 Findeis, M.A. and Kaiser, E.T., Nitrobenzophenone Oxime Based Resins for the Solid-Phase Synthesis of Protected Peptide Segments, J. Org. Chem., 54 (1989) 3478-3482. 

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