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Kainate receptors, iGluR

More than 20 different mammalian iGluR subunits have been identified. These form receptors that fall into three major categories based on the characteristics of activation by different agonists (1) kainate receptors... [Pg.314]

Fig. 1. Domain structure of ionotropic glutamate receptors (iGluRs) showing the four major components of mammalian iGluRs and the transmembrane topology. Bacterial iGluRs do not have the ATD and the C-terminal domain, and kainate binding proteins from lower vertebrates do not have the ATD. Note that SI and S2 refer to segments of the primary sequence whereas, Lobes 1 and 2 refer to protein folding units. Both Lobes 1 and 2 are made up of pordons of both SI and S2. Fig. 1. Domain structure of ionotropic glutamate receptors (iGluRs) showing the four major components of mammalian iGluRs and the transmembrane topology. Bacterial iGluRs do not have the ATD and the C-terminal domain, and kainate binding proteins from lower vertebrates do not have the ATD. Note that SI and S2 refer to segments of the primary sequence whereas, Lobes 1 and 2 refer to protein folding units. Both Lobes 1 and 2 are made up of pordons of both SI and S2.
Glutamate is an excitatory neurotransmitter that acts upon the glutamatergic receptors," comprised of two classes metabotropic (mGluRs) and ionotropic (iGluRs). The iGluRs are classified further by their selective agonists kainate, NMDA (A -methyl... [Pg.271]

See other pages where Kainate receptors, iGluR is mentioned: [Pg.47]    [Pg.1786]    [Pg.449]    [Pg.315]    [Pg.183]    [Pg.150]    [Pg.42]    [Pg.873]    [Pg.852]    [Pg.315]    [Pg.143]    [Pg.10]    [Pg.57]    [Pg.429]    [Pg.457]    [Pg.315]    [Pg.316]    [Pg.319]    [Pg.315]    [Pg.316]    [Pg.319]   
See also in sourсe #XX -- [ Pg.315 , Pg.331 ]

See also in sourсe #XX -- [ Pg.315 , Pg.331 ]



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Kainate

Kainate receptors

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