Joyce, Gerald

Almost 20 years ago, in a review article in Nature, Gerald Joyce (1989) explained why RNA fulfils almost ah the conditions which a type of substance requires in order to be able to transfer information ... 

Jeff Rogers and Gerald F. Joyce (1999) studied the question as to whether a ribozyme containing only three different types of nucleotide rather than the normal four can also be catalytically active. They decided that the nucleoside cytidine (with the base cytosine) should be eliminated, for two reasons ... 

This creates a dilemma of a different sort. How are we to demonstrate ribozyme activities that no longer exist Perhaps we must design our own ribozymes to demonstrate the full potential for RNA to act as an enzyme. This approach is being used by Jack Szostak and Gerald Joyce, who indepen-... 

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