Joint Replacements Do Not Last Forever

Wear of UHMWPE is cmrently recognized as the primary culprit responsible for aseptic loosening and late revision of hip replacements. Researchers have estimated that for each day of patient activity, around 100 million microscopic UHMWPE wear particles are released into the tissues surrounding the 

Example of an osteolytic lesion in the pelvis, located superior to the metal-backed acetabular component. (Courtesy of Av Edidin, Ph.D., Drexel University.) 

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