Jec-Butylamine

Yun, H., Cho, B.-K. and Kim, B.-G., Kinetic resolution of (R,S)-jec-butylamine using omega-transaminase from Vibrio fluvialis JS17 under reduced pressure. Biotechnol. Bioene., 2004, 87, 772-778. 

Problem 18.11 There is no change in the configuration of the chiral C in jec-butylamine formed from the Hofmann degradation of (5 )-2-methylbutanamide. Explain. <... 

The synthesis of butralin (dibutalin, 3) starts with 4-/-butylphenol, the nitration of which with a mixture of nitric acid and acetic acid gives 4-t-butyl-2,6-dinitrophenol in a good yield. The dinitrophcnol is reacted in dimethyl formamide solution with phosphorus oxychloride to give l-/-butyl-4-chloro-2,6-dinitro-benzene. The reaction of the latter with jec-butylamine gives butralin (Bishop el al.,... 

Under similar conditions ethyl methyl ketone gives 90% of jec-butylamine, 2-heptanone gives 90% of 2-heptanamine, and at 150770 atm even diisobutyl ketone gives 48% of the corresponding amine.886... 

The reaction of DHA with primary amines having only one or no a-protons, such as isopropyl-, jec-butyl-, or Zerr-butylamine, gave spectra... 

Ai-Butylalcohol, EMA resin esterification, 434 jec-Butylalcohol, EMA resin esterification, 434 /-Butylalcohol, EMA resin esterification, 434 Butylamine, SMA resin reaction, 430 r-Butylbenzene, 199, 200 MA CTC, 210... 

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