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Isotopes in biosynthetic studies

Several useful reviews have appeared on the use of stable isotopes in biosynthetic studies [122,123,125,126,203-206], and on the instrumental methods employed [207]. The techniques will be illustrated in this section by a number of examples. [Pg.42]

Table 12. Spectroscopic techniqpies used for the detection of stable isotopes in biosynthetic studies... Table 12. Spectroscopic techniqpies used for the detection of stable isotopes in biosynthetic studies...
Stable Isotopes in Biosynthetic Studies Table 4 N.m.r. data for mollisin... [Pg.247]

General.—Since the electron-impact fragmentation patterns of many classes of natural products are now known, mass spectrometry can be used in conjunction with heavy isotopes in biosynthetic studies. A study of the fragmentation pattern of a metabolite with and without isotopic labelling yields direct information on the position of the labelled atom in the molecule without recourse to wet chemical degradation. Essential requirements for the biosynthetic application of mass spectrometry are (0 thermal stability of the metabolite at the probe inlet temperatures and (ii) a reasonably simple fragmentation pattern. [Pg.288]

See other pages where Isotopes in biosynthetic studies is mentioned: [Pg.919]    [Pg.257]    [Pg.324]    [Pg.241]    [Pg.243]    [Pg.245]    [Pg.249]    [Pg.251]    [Pg.253]    [Pg.255]    [Pg.257]    [Pg.259]    [Pg.261]    [Pg.263]    [Pg.267]    [Pg.269]    [Pg.271]    [Pg.273]    [Pg.275]    [Pg.277]    [Pg.281]    [Pg.283]    [Pg.285]    [Pg.287]    [Pg.289]    [Pg.291]    [Pg.293]    [Pg.295]    [Pg.297]    [Pg.299]   
See also in sourсe #XX -- [ Pg.1092 ]

See also in sourсe #XX -- [ Pg.1092 ]

See also in sourсe #XX -- [ Pg.1092 ]

See also in sourсe #XX -- [ Pg.1033 ]

See also in sourсe #XX -- [ Pg.1097 ]

See also in sourсe #XX -- [ Pg.1012 ]



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Isotopic labelling use in biosynthetic studies

STABLE ISOTOPES IN THE STUDY OF BIOSYNTHETIC PATHWAYS

Stable Isotopes in Biosynthetic Studies

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