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Isothiocyanate synthesis, quinoline

The schemes presented below also illustrate the synthesis of various amides of substituted quinoline-and quinolonecarboxylic acids 212-214 by the reaction of isatins 7, 9, 54, and 180 with amides 215 [179], acylated amino acids 216 and isothiocyanates [182], and enamines 217 [183],... [Pg.32]

AllenylHthium compounds can function as nucleophiles for the synthesis of quinolines. The reaction of 3-methyl-1,2-butadienyllithium with phenyl isothiocyanate in THF at -70 C produces the allenyl thio-carboximidate, which can be thermally cyclized to 2-methylthioquinoline (Scheme 14). ... [Pg.86]

See other pages where Isothiocyanate synthesis, quinoline is mentioned: [Pg.231]    [Pg.412]    [Pg.412]    [Pg.235]    [Pg.368]    [Pg.310]    [Pg.516]    [Pg.518]    [Pg.416]   
See also in sourсe #XX -- [ Pg.578 ]



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