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Isothiazoles halogen-metal exchange

Halogen-metal exchange has also been used to give a 5-lithioisothiazole derivative (73JMC978), but this route appears to offer no advantage over direct metalation. However, direct metalation of 3,5-disubstituted isothiazoles at the 4-position has not been reported, and in this case halo-... [Pg.215]

See other pages where Isothiazoles halogen-metal exchange is mentioned: [Pg.873]    [Pg.894]    [Pg.873]    [Pg.894]    [Pg.165]    [Pg.873]    [Pg.894]    [Pg.873]    [Pg.894]   
See also in sourсe #XX -- [ Pg.490 ]



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