Isothermal titration calorimetry experimental design

Freyer, M. W., Lewis, E. A. (2008). Isothermal titration calorimetry experimental design, data analysis, and probing macromolecule/ligand binding and kinetic inteac-tions. Methods Cell Biol., 84, 79-113. 

Despite the great diversity in the design of microcalorimeters and the experimental procedures described in the literature [1-10], only two microcalorimetric methods have found widespread application in cydodextrin (CyD) studies and drug-design research. These two methods are differential scanning calorimetry (DSC) and isothermal titration microcalorimetry (ITC). DSC and ITC can be con-... 

---