Isopropanol serum osmolality

Table 58-2 lists the concentration and expected contribution to the serum osmolality in ethanol, methanol, ethylene glycol, and isopropanol poisonings. 

The presence of isopropanol in the blood will result in an increase in the serum osmolality without a concurrent metabolic acidosis. The measured serum osmolality represents the summation effect of both isopropanol and acetone. 

Monaghan MS, Ackerman BH, Olsen KM, et al. Use of delta osmolality to predict serum isopropanol and acetone concentrations. Pharmacotherapy 1993 13(1) 60-63. 

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