Isoindole-l ,3-

Octahydrobicyclo[4.3.0]nonane-3,4-dicarboxylic imide CA name) decahydrocydopent[/]isoindole-l,3-dione (fusion name)... 

AZIRIDINE, trans-l-ammo-2,3-diphenyl-[1-Azindinamme, trans-(i)-2,3-di-phenyl-], 55,53, 114 AZIRIDINE, frans-2,3-diphenyl-l-phthal-linido- [ l//-Isoindole-l,3(2//)-dione, trans-( )-2-(2,3-diphenyl-1 -azindin-yl) 1,55, 115... 

CN (3aa,4p,7p,7aa)-hexahydro-2-[4-[4-(2-pyriniidinyI)-I-pipera2inyI]butyI]-4,7-methanO lA/-isoindole-l,3(2//)-dione... 

The hydrogenated compound, eAo-hexahydro-4.7-methano-2-phenyl-l/7-isoindole-l,3(2//)-dione, has also been used. Thus, treatment with 2.5 equiv of LDA in THF at — 80 X for 30 min, followed by addition of CH31 (— 80 - +25 X), resulted in a 55% yield of e (fo-hexahydro-4,7-methano-3a,7a-dimethyl-2-phenyl-lF7-isoindole-l,3(2/7)-dione mp 115 — 117 X. 

Chemical Name lH-Isoindole-l,3(2H)-dione, 2-(5-(4-aminophenoxy) pentyl)-... 

Chemical Name N-(trichloromethylthio)cyclohex-4-ene-l,2-dicarboximide l,2,3,6-tetrahydro-/V-(trichloromethyl-thio)phthalimide 3a,4,7,7a-LeLrahydro-[(trichloromeLhyl)thio]-l//-isoindole-l,3(2//)-dione CAS Registry No 133-06-2... 

Synonym ENT-26539, Faltan, Folpan, Folpel, Ftalan, Fungitrol, Orthophaltan, Phaltan, Spolacid, Thiophal, Vinicoll Chemical Name V-(trichloromethylthio)phthalimide 2-[(trichloromethylthio]-l/f-isoindole-l,3(2//)-dione CAS Registry No 133-07-3... 

Lupetidine Piperidine, C,C -dimethyl- Phthalimide 17/-Isoindole-l,3(27/)-dione... 

SYNS HYDROXYMETHYLPHTHALIMIDE IH-ISOINDOLE-l,3(2H)-DIONE, 2-(HYDROXYMETHYL)- N-METHYLOLPHTHALIMIDE OXYMETHYLPHTH-ALIMIDE PHTHALIMIDE, N-(HYDROXYMETHYL)- PHTHALIMIDOMETHYL ALCOHOL... 

SYNS FOLPAN FOLPET FTALAN ORTHO-PHALTAN PHALTAN PHTHALTAN THIOPHAL N-(TRICHLOR-METHYLTHIO)-PHTHALAMID -(GERMAN) N-(TRICHLOROMETHYLMERCAPTO)-PHTHAUMIDE 2-((TRICHLOROMETHYL)THIO)-lH-ISOINDOLE-l,3(2H)-DIONE TROYSAN ANTIMILDEW O... 

DIOXO-3-PHTHALIMIDOPIPERlDINE see TEH500 2-(2-6-DIOXO-3-PIPERlDINYL) 1H-ISOINDOLE-l,3(2H)-DIONE see TEH500 N-(2,6-DIOXO-3-PIPERlDYL)PHTHALIMIDE see TEH500... 

Synonym 3a,4,7,7a-Tetrahydro-2-[(l,l,2,2-tetra-chloroethyl)thio]-lH-isoindole-l,3(2H)-dione Chemical/Pharmaceutical/Other Ceass Phthali-mide fungicide Chemical Structure ... 

Keywords 3,4-bis(diphenylmethylene)-A/ -methylsuccimide, [4+2]photodimeri-zation cyclization, 2-methyM,4,9-triphenyl-3a,4-dihydro-benzo[f]isoindole-l, 3-dione... 

Even though it has been known for 100 years or more that stereoselectivity plays an important role in drug activity, chiral drugs have been developed and used as race-mates while neglecting the fact that they comprise mixtures of two or more compounds that may have quite different pharmacological properties [98,99]. An example with dramatic consequences is Thalidomide (2-(2,6-dioxo-3-piperidyl)isoindol-l,3-dion, Contergan). 

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