Isoindole catalytic reduction

Vigorous catalytic reduction of indole (H2/Pd/AcOH/HCI, 80°C) results in the formation of cis-octahydroindole. Catalytic reduction of isoindoles occurs in the pyrrole ring. Reduction of indolizine with hydrogen and a platinum catalyst gives an octahydro derivative. With a palladium catalyst in neutral solution, reduction occurs in the pyridine ring but in the presence of acid, reduction occurs in ... 

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