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Isogenic cell lines

Activating Ras mutations have been found in more than 25% of human tumors. However, a drug-like small molecule inhibitor for Ras protein is not currently available. Several synthetic lethal screens have been carried out using isogenic cell lines for Ras. Torrance et al. conducted a synthetic lethal screen of a library of about 30,000 compounds and identified some novel hits including... [Pg.130]

Yamamoto KN, Hirota K, Kono K, Takeda S, Sakamuru S et al (2011) Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines. Environ Mol Mutagen 52 547-561... [Pg.329]

SOMAMOTO T, NAKANISHI T, OKAMOTO N (2000), Specific ceU-mediated cytotoxicity against a virus-infected syngeneic cell line in isogeneic ginbuna crucian carp , Dev Comp Immunol, 24, 633-40. [Pg.63]


See other pages where Isogenic cell lines is mentioned: [Pg.222]    [Pg.98]    [Pg.100]    [Pg.131]    [Pg.132]    [Pg.172]    [Pg.222]    [Pg.98]    [Pg.100]    [Pg.131]    [Pg.132]    [Pg.172]    [Pg.233]    [Pg.332]    [Pg.130]    [Pg.130]    [Pg.132]    [Pg.301]    [Pg.363]    [Pg.250]    [Pg.189]    [Pg.310]    [Pg.1984]    [Pg.367]    [Pg.63]    [Pg.226]    [Pg.97]    [Pg.18]    [Pg.323]    [Pg.115]    [Pg.2205]    [Pg.413]    [Pg.80]    [Pg.30]    [Pg.254]    [Pg.172]    [Pg.79]   
See also in sourсe #XX -- [ Pg.98 , Pg.100 , Pg.130 , Pg.131 ]




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