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Isocratic SMB Chromatography

Conventional Isocratic SMB ChromatographY 473 time can be calculated according to Equation 7.107 ... [Pg.473]

Isocratic SMB ChromatographY under Variable Operating Conditions 481... [Pg.481]

Isocratic SMB Chromatography under Variable Operating Conditions... [Pg.481]

Gradient elution chromatography is a separation method that exploits the effect of the fluid phase composition on the retention behavior of the feed components. It is widely used, especially for analytical separations in the areas of the life sciences, in biochemistry, and in the biotechnologies e.g., separation of complex mixtures of proteins or peptides), hi its conventional implementations, SMB units are operated under isocratic conditions. The composition of the fluid phase, e.g., the organic modifier concentration, the pH, or the buffer concentration remain constant in all the sections of the SMB unit. However, it has recently been shown that SMB units can also be operated under solvent gradient mode (SG-SMB). Then, the feed and desorbent streams introduced have a different composition. The fluid phase composition is different in each section. It is chosen independently, in order to... [Pg.827]

See other pages where Isocratic SMB Chromatography is mentioned: [Pg.461]    [Pg.461]    [Pg.463]    [Pg.465]    [Pg.467]    [Pg.469]    [Pg.471]    [Pg.475]    [Pg.477]    [Pg.479]    [Pg.461]    [Pg.461]    [Pg.463]    [Pg.465]    [Pg.467]    [Pg.469]    [Pg.471]    [Pg.475]    [Pg.477]    [Pg.479]    [Pg.212]    [Pg.201]    [Pg.5]    [Pg.286]    [Pg.294]    [Pg.208]    [Pg.204]    [Pg.5]   


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Isocratic

Isocratic chromatography

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