Isis Innovation Limited

One approach developed by Isis Innovation Limited (a wholly-owned subsidiary of the University of Oxford) involves the precipitation of calcium phosphate onto collagen at room temperature. When o-phosphoserine is added to the reaction, the calcium phosphate precipitates onto the collagen in the form of small "needles." These structures provide abundant surface area on which osteoblasts and other hone cells can become established. 

C. J. Kepert and M. J. Rosseinsky, Porous solid products of 1,3,5-benzenetricarboxylate and metal ions, (Isis Innovation Limited, UK). 1999,98-GB2213,9905151... 

Innovative design concepts while no final judgement on particular improved design concepts was possible, the participants agreed that emphasis should be put on the study of those innovative concepts that can facilitate leak detection, ISI, and limit core flow reduction in the DEGR. In this context, it is useful to consider the double wall concept adopted for Russian reactors (BN-600). 

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