Iodobenzene 2,4,6-trimethyl

Of all the palladium-catalyzed coupling reactions, the Kumada coupling has been applied least often in indole chemistry. However, this Grignard-Pd cross-coupling methodology has been used to couple l-methyl-2-indolylmagnesium bromide with iodobenzene and a-bromovinyltrimethylsilane to form l-methyl-2-phenylindole and l-methyl-2-(l-trimethyl-... 

The first catalytic version of the Hofmann rearrangement using aryl iodides as catalysts and mCPBA as terminal oxidant was reported by Ochiai and coworkers in 2012 [72], A study of the catalytic efficiency of substituted iodobenzenes and some aliphatic alkyl iodides in the iodane(III) catalyzed Hofmann rearrangement of benzylic carboxamides has demonstrated that iodobenzene is the best catalyst. The introduction of both electron-donating (4-methyl, 3,5-dimethyl and 2,4,6-trimethyl) and electron-withdrawing groups (4-Cl and 4-CF3) into iodobenzene decreased the yield of rearranged products. Aliphatic iodides such as methyl, trifluoroethyl and 1-adamantyl iodides showed no catalytic efficiency. Under optimized reaction conditions,... 

New methods for preparing known selenium reagents are always interesting. For example, phenyl selenocyanate is readily prepared by addition of trimethyl-silylcyanide to phenylselenyl chloride. Two new preparations of sodium phenylselenide have also appeared. In the first, selenide ion is photolysed in the presence of iodobenzene, whereas the second preparation involves... 

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