Intracellular Ca2+ Fluxes

There is also ample evidence that intracellular Ca2+ fluxes are involved in TRH action. However, the relative importance of stimulus-evoked increase of extra- and intracellular Ca2+ seems to be different for PRL and TSH release. Geras et al. reported that TRH increased Ca2+ uptake in thyrotropic tumor cells (TtT cells) but not in PRL-secreting GH3 cells [67] whereas verapamil had no effect on TRH-stim-... 

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