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Interference with second messenger pathways

Cholera toxin interferes with the function of a key G-protein in the small intestine by deactivating its intrinsic GTPase activity. The consequence is uncontrolled activation of the signal transduction pathway which produces the second messenger 3, 5 -cyclic AMP leading to a life-threatening diarrhea following the activation of ion and water secretion. [Pg.186]

See other pages where Interference with second messenger pathways is mentioned: [Pg.58]    [Pg.500]    [Pg.971]    [Pg.971]    [Pg.1370]    [Pg.16]    [Pg.348]    [Pg.197]    [Pg.453]    [Pg.318]    [Pg.209]    [Pg.4126]    [Pg.502]   
See also in sourсe #XX -- [ Pg.17 ]



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Interference with second messenger

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