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Interconversion between loading, maintenance, oral and intravenous bolus doses

10 Interconversion between loading, maintenance, oral and intravenous bolus doses [Pg.253]

Equations 12.42 through 12.53 allow movement back and forth between loading dose (Dl), maintenance dose (Dm) an oral dose and an intravenous bolus dose. [Pg.253]

A note of caution. Not all of these equations may be safely rearranged algebraically. Rearrangement is unnecessary as there are equations ready made for any conversion required. For example, Eq. 12.42 should not be rearranged in order to solve for (Dm)iv from a known (DM)otai- Instead, Eq. 12.43 is used, which already is in the form [Pg.253]

Dangerous fluctuation may occur in the PO IV conversion direction Use IV PO only. [Pg.254]




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Loading doses

Oral doses

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