Interchromatin granule clusters

Current textbook descriptions of nuclear structure typically describe interphase nuclear organization as divided into heterochromatin and euchromatin compartments, where the heterochromatin corresponds to densely, heavy metal-stained masses, frequently adjacent to the nuclear envelope or nucleolus, and the euchromatin corresponds to the lighter stained, more finely textured regions lying between the heterochromatin and other identifiable, subnuclear compartments, such as the nucleolus or interchromatin granule clusters. 

Fig. 11. A. Typical aspect of a cluster of interchromatin granules in normal rat liver nucleus. Glutaraldehyde>Epon, EDTA method chr, bleached chromatin ->, perichromatin granules fibrils ig interchromatin granules. X42,300. B. Cluster of interchromatin granules in the nucleus of an adrenal cortex cell from normal rat. Glutaraldehyde-Epon, EDTA method. The granules are irregularly shaped and have a striking tendency to form chainlike aggregates. small rods may be found,...

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