Injectable composites fibrin

Cui, G., Li, J., Lei, W. et al. 2010. The mechanical and biological properties of an injectable calcium phosphate cement-fibrin glue composite for bone regeneration. / Biomed Mater Res B 92B 377-85. 

Fabrication of the new 3 dimensional scaffold was by mixing the two materials in different compositions (Table 1). The Fibrin gel was formed by injecting a mixture of 50 mg/ml of HAM and 50 mg/ml of fibrinogen suspension with 10 U of thrombin-CaCli solution simultaneously into a 70 mm x 50 mm custom made 316L mold (Figure 2). The mold was incubated for 45 minutes in the incubator (37° C, 5% CO2) before the transfer of the formed construct to a 24-weU plate (Figure 3). 

---