INHIBCONT - Continuous Bioreactor with Inhibitory Substrate

2 INHIBCONT - Continuous Bioreactor with Inhibitory Substrate 

Inhibitory substrates at high concentrations reduce the specific growth rate below that predicted by the simple Monod equation. The inhibition function may often be expressed empirically as 

A continuous inhibition culture will often lead to two possible steady states, as defined by the steady-state condition p = D, as shown in Fig. 2. 

5 Simulation Tools and Examples of Chemical Engineering Processes 

One of these steady states (A) can be shown to be stable and the other (B) to be unstable by reasoning somewhat similar to that described in Sec. 3.2.7. Thus only state A and the washout state (S = Sq) are possible. Using simulation techniques, the behaviour of the dynamic approach to these states can be investigated. 

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