Inflammatory cardiac disorders

Stroke in the context of preceeding malaise for up to some months suggests an inflammatory arterial disorder, particularly giant cell arteritis, infective endocarditis, cardiac myxoma, cancer, thrombotic thrombocytopenic purpura or even sarcoidosis (Ch. 6). 

Fever is unusual in the first few hours after stroke onset, and endocarditis or other infections, inflammatory vascular disorders or cardiac myxoma should be considered. Later fever is quite common and usually reflects a complication of the stroke (Ch. 16). 

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