Inflammatory activities, QSAR

Du Toil, K. Elgorashi, E. E. Malan, S. F Drewes, S. E. Van Staden, J. Crouch, N. R. Mulholland, D. A. Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachieulenus longiflorus Griseb. (Gentianaceae). Bioorg. Med. Chem. 2005,13, 2561-2568. 

Vicini et al. reported on the preparation of hydrazones 234 obtained from the condensation of a proper aldehyde with 1,2-benzisothiazole hydrazide derivatives 233 characterised by a different length of the linker chain (Scheme 59) [70] and their antimicrobial [71,72] and anti-inflammatory [73] activities were evaluated. Both theoretical and experimental hpophilic indices were calculated and QSAR studies were also reported [70]. 

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