Inflammation/inflammatory processes beneficial effects

It makes little sense to combine tretinoin with a topical corticosteroid to limit the inflammatory reaction. It may well be that this combination is supposed to stop inflammation, but inflammation is beneficial in that it stimulates the process of skin repair, furthermore, the combined effect of corticosteroid and tretinoin could potentially cause telangiectasia. The tretinoin would stop skin atrophy as a result of the application of topical corticosteroid, whereas it should increase the thickness of the epidermis overall. A large part of the effect would therefore be lost, finally, corticosteroids should not be applied to the skin for a prolonged period, whereas long-term application of tretinoin is necessary. 

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